Latrogenic platelet dysfunction: an emerging peril
Wolfe, S.A.; Lian, E.C.
Plastic and Reconstructive Surgery 55(5): 602-605
1975
ISSN/ISBN: 0032-1052 PMID: 1144537 Document Number: 93774
Abnormal bleeding after a face lift was found to be due to a profound interference in platelet function caused by clofibrate and xylocaine acting synergistically. This did not appear to be an idiosyncratic reaction to either of the drugs, as it could be reproduced in vitro by using platelets from normal individuals. Clofibrate is a drug used commonly by persons in the age group requesting face lifts. Beware.