A study of hydrocortisone metabolism in dogs by the liver perfusion method
Tron'ko, M.D.; Gorban', I.M.
Fiziolohichnyi Zhurnal 21(4): 462-465
1975
ISSN/ISBN: 0015-3311 PMID: 1218639 Document Number: 91063
The dog liver perfused in situ is capable of metabolizing hydrocortisone and secreting the following metabolites into the perfusate: tetrahydrocortisol, tetrahydrocortisone, cortisone, etc. The in situ perfusion method is a convenient model for studying metabolism of steroid hormones.
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