Concurrence of ulcerative colitis and chronic acitve hepatitis, Clinical courses and results of colectomy
Olsson, R.; Hultén, L.
Scandinavian Journal of Gastroenterology 10(3): 331-335
1975
ISSN/ISBN: 0036-5521 PMID: 1079628 Document Number: 90804
Seven patients with coexisting chronic active hepatitis and ulcerative colitis are reviewed. The activity of the two diseases varied independently. Proctocolectomy was necessitated in 6 patients and was followed by disappearance or decreased in titres of smooth muscle and antinuclear autoantibodies and immunoglobulins and, in one patient, by a rapid normalization of markedly elevated transaminases. Although the series are small, we feel that our data suggest that proctocolectomy for severe ulcerative colitis may have some beneficial effect on a coexisting chronic active hepatitis.