Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effects of long-term rotation and hypergravity on developing rat femurs

Smith, S.D.

Aviation Space and Environmental Medicine 46(3): 248-253

1975

ISSN/ISBN: 0095-6562
PMID: 1115727
Document Number: 90524
Male and female Sprague-Dawley rats derived from a single mating were raised for three generations under constant centrifugation at 1.03 G (Rotation Controls) and at 2 G. When the third generation rats were 3 months old, they were sacrificed, and their femurs removed. After fixation and cleaning, the femurs were then measured for length and diameter. Then right femurs were sectioned longitudinally, left femurs transversely. After staining with Hematoxylin and Eosin, right femurs were examined for ossification patterns and left femurs were measured for cortical thickness. All rotation control rats showed marked stimulation of ossification in the femoral head, and males showed significant cortical thinning when compared to non-rotated earth gravity controls. All 2 G femurs showed decreased length and aspect (L/D) ratios, and increased cortical thickness/diameter ratios when compared to earth controls or rotation controls. Ossification of the femoral head was slightly advanced, while the distal epiphyseal plate was thinned.

Document emailed within 1 workday
Secure & encrypted payments

Maurat, J.P.; Bugnon, C.; Rousselet, F.; Fellmann, D.; Becque, O.; Techenet, P. 1978: Effect of long-term phenytoin treatment on the levels of calcium and magnesium in rat femurs Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 172(6): 1114-1118
Cai, Y.; Hao, M.-D. 2013: Effects of long-term rotation on the nutritional quality of wheat grain protein on dryland of Loess Plateau, Northwest China Ying Yong Sheng Tai Xue Bao 24(5): 1354-1360
Tylman, D.; Siwek, W. 1991: Long-term results of functional treatment in intraarticular knee fractures and multifragment fractures of the shaft of femurs Clinical Orthopaedics and Related Research 272: 114-121
Chang, Y.-C.; Huang, C.-C.; Huang, S.-C. 2008: Long-term neuroplasticity effects of febrile seizures in the developing brain Chang Gung Medical Journal 31(2): 125-135
Li, N.; Lee, R.; Gerland, P. 2013: Extending the Lee-carter method to model the rotation of age patterns of mortality decline for long-term projections Demography 50(6): 2037-2051
Xu, Y.; Shen, Q.; Lei, B. 2000: Effect of long-term no-tillage and application of organic manure on some properties of soil fertility in rice/wheat rotation Ying Yong Sheng Tai Xue Bao 11(4): 549-552
Konat, G.; Clausen, J. 1974: The effect of ?long-term administration of triethyl lead on the developing rat brain Environmental Physiology and Biochemistry 4(5): 236-242
Gerowitt, B.; Bodendorfer, H. 2001: Long-term population development of Viola arvensis Murray in a crop rotation. II. Modelling population development Zeitschrift für Pflanzenkrankheiten und Pflanzenschutz (1970) 108(3): 269-283
Gerowitt, B.; Bodendorfer, H. 2001: Long-term population development of Viola arvensis Murray in a crop rotation. II. Modelling population development Zeitschrift für Pflanzenkrankheiten und Pflanzenschutz (1970) 108(3): 269-283
Hall, J.W.; Grose, J.H. 1993: Short-term and long-term effects on the masking level difference following middle ear surgery Journal of the American Academy of Audiology 4(5): 307-312
Bala, Y.; Dhall, G.I.; Majumdar, S. 1991: Short-term and long-term effects of norplantR-2 on plasma lipoproteins and glucose tolerance Advances in Contraception 7(1): 77-83
Nemoto, A.; Uemura, T. 2000: Hypergravity effects on osteoclasts activity Journal of Gravitational Physiology: a Journal of the International Society for Gravitational Physiology 7(2): P127-P128
Bryson, G.; Reynolds, R.W. 1981: Effects of adrenocortical stress responses and metabolic functions during and after long-term administration of dexamethasone to adult Evans-Long rats Research Communications in Chemical Pathology and Pharmacology 34(2): 267-286
Ockene, J.K.; Kristeller, J.; Pbert, L.; Hebert, J.R.; Luippold, R.; Goldberg, R.J.; Landon, J.; Kalan, K. 1994: The physician-delivered smoking intervention project: can short-term interventions produce long-term effects for a general outpatient population? Health Psychology: Official Journal of the Division of Health Psychology American Psychological Association 13(3): 278-281
Li, L.; Li, Y-Q.; Liu, B.; Wang, H.; Zhang, D-M. 2017: Short-term and long-term effects of covered stent endovascular graft exclusion for the treatment of abdominal aortic aneurysm rupture European Review for Medical and Pharmacological Sciences 21(3 Suppl): 73-77
Adamian, A.A.; Gliantsev, S.P. 1992: Long-term multicomponent enzyme therapy--a developing trend in the complex treatment of suppurative wounds Khirurgiia 1992(7-8): 105-114
Dück, K.D.; Richard, F. 1990: Long-term nitrate therapy in coronary heart disease--loss of effect by developing tolerance Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 45(24): 736-741
Oon, C.J.; Chan, S.H.; Chiang, S.C.; Chio, L.F.; Chua, K.L.; Yo, S.L. 1980: Primary hepatocellular carcinoma developing in a female patient on long term oral contraceptives--a case report Annals of the Academy of Medicine Singapore 9(3): 402-404
Price, T.R. 1982: Short- and long-term cognitive effects of ECT: Part I--Effects on memory Psychopharmacology Bulletin 18(2): 81-91
Di, Z.; Jiang, S.; Lin, X.-M.; Fu, W.-B. 2014: The short-term and long-term effects on neck pain caused by cervical spondylosis treated with combination of acupuncture and moxibustion with seed-sized moxa cone Zhongguo Zhen Jiu 34(4): 325-328