Anti-inflammatory activity of thiabendazole and its relation to parasitic disease
van Arman, G.G.; Campbell, W.C.
Texas Reports on Biology and Medicine 33(2): 303-311
1975
ISSN/ISBN: 0040-4675 PMID: 127396 Document Number: 89827
In assays with laboratory animals thiabendazole has been found to have anti-inflammatory activity. This finding supports clinical suggestions that the drug exhibits anti-inflammatory properties in man. These may contribute to the clinical response observed following the use of thiabendazole in cases of trichinelliasis, cutaneous and visceral larval migrans, and dracunculiasis. In parasitic infections in which corticosteroids are commonly used in clinical management, notably trichinelliasis, the fact that thiabendazole does not appear to have immunosuppressive activity may confer an added clinical advantage. [AS].