Epidermal growth factor receptor (EGFR) inhibitor associated skin eruption
Seiverling, E.V.; Fernanadez, E.M.; Adams, D.
Journal of Drugs in Dermatology Jdd 5(4): 368-369
2006
ISSN/ISBN: 1545-9616 PMID: 16673807 Document Number: 8872
EGFR Inhibitors are used to treat Non-Small-Cell Lung Cancer (NSCLC) and colorectal cancer (CRC). A common side effect of EGFR Inhibitors is a follicular/pustular skin eruption. We report a case of gefitinib (Iressa) associated skin eruption. The treatment regimen consisted of triamcinolone 0.1% cream twice daily, clindamycin 1% lotion twice daily and sodium sulfacetamide lotion twice daily. The clinical presentation, etiology, and management options of EGFR Inhibitor associated skin eruptions are discussed.
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