Inhibition of Deamination of Arabinosylcytosine (NSC-63878) by Rhodium (II) Acetate

Lee, S.H.; Chao, D.L.; Bear, J.L.; Kimball, A.P.

Cancer ChemoTherapy Reports 59(3): 661-663

1975


ISSN/ISBN: 0069-0112
PMID: 1203890
Document Number: 88352
The nobel metal "cage" complex, rhodium(II) acetate, was found to inhibit the deamination of the fraudulent nucleoside, arabinosylcytosine. Potent inhibition of a purified cytidine deaminase from mouse kidney was observed when either cytidine or arabinosylcytosine was used as substrate.

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