Duration of oculomotor akinesia of injectable anesthetics
Everett, W.G.; Vey, E.K.; Finlay, J.W.
Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology 65: 308-315
1961
ISSN/ISBN: 0002-7154 PMID: 13697649 Document Number: 8748
The duration of akinesia produced by retrobulbar injection of the common anesthetic agents was measured, using optokinetic nystagmus in the Rhesus monkey as a criterion. The effects of hyaluronidase and/or epinephrine with procaine as noted in this study confirm observations by others. A new agent, Carbocaine (brand of mepivacaine), was found to produce an excellent duration of akinesia with no tissue irritation when used for retrobulbar injection. Epinephrine and hyaluronidase did not appear to improve its effectiveness.
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