New sequential therapy in the premenopause
Conrad, K.H.; Heinen, G.
Medizinische Klinik 70(13): 558-562
1975
ISSN/ISBN: 0025-8458 PMID: 1094252 Document Number: 87411
The treatment of 85 women in the premenopause during 387 cycles is reported. Sequential therapy in the form of conjugated Estrogens (Presomen) and a new synthetic Gestagen, was given in 3 different modifications: from the 5th to the 24th day of the cycle 1.25 mg Presomen a day, additionally on the last 5, 7, or 10 days, during each period 6, respectively, 5 mg Gestagen a day. Both the dysfunctional hemorrhages as well as the climacteric syndrome, were favorably influenced. The mode 10 + 10 days, i.e., 10 days Estrogens alone + 10 days combined with Gestagen, proved best. A sufficiently secure contraception is not guaranteed. This can e recognized by the occurrence ob biphasic basal temperature curves.