Yin-yang strategy: proposing a new, effective, repeatable, sequential therapy for psoriasis
Bhutani, T.; Zitelli, K.B.; Koo, J.
Journal of Drugs in Dermatology Jdd 10(8): 831-834
2011
ISSN/ISBN: 1545-9616 PMID: 21818503 Document Number: 16120
Psoriasis is a chronic disease that exists in two phases: (1) the acute, flaring phase when psoriasis is highly inflamed, erythematous and pruritic and (2) the chronic, indolent phase after the acute manifestations are brought under control. Ideal therapies for psoriasis must focus on both of these phases. Therefore, a rapid and effective agent must be utilized to treat the acute phase, followed by safe long-term therapy for maintenance. This article proposes a new, effective sequential topical therapy for psoriasis using ongoing treatment with clobetasol (Clobex®) spray for one month followed by calcitriol (Vectical®) ointment for the next month. This strategy provides a highly effective, reliable and safe treatment option with minimal local and systemic adverse risks.
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