Quantitative description of the adaptation of vagal effects by means of an electromechanical coupling model
Nilius, B.; Koester, G.
Acta Biologica et Medica Germanica 34(8): 1377-1386
1975
ISSN/ISBN: 0001-5318 PMID: 1210998 Document Number: 86783
A four compartments model describes the electrotropic and the inotropic vagal effect time courses during long time stimulation. The model realises electro-mechanical coupling. A differential equation for the coupling model is developed, solutions are given and a numerical treatment is described. The model shows the essential properties of effect adaptation: time delay and smaller extent of electrotropic effect adaptation.
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