Use of propranolol in permanent essential hypertension
Safar, M.; Weiss, Y.; Simon, A.; Lehner, J.P.; Milliez, P.
Annales de Medecine Interne 126(11): 737-743
1975
ISSN/ISBN: 0003-410X PMID: 1211699 Document Number: 86606
The anti-hypertensive effect of propranolol is studied in 35 essential permanent hypertensive patients. The decrease in blood pressure in higher in the presence (p is less than 0.01) than in the absence of diuretic therapy. The anti-hypertensive effect is higher in severe than in moderate hypertension. No side effect was observed except the decrease in heart rate (p is less than 0.001). Dihydralazine was added in 4 severe hypertensive patients and induced in 2 of them anginal attacks.