Neutropenia in disorders of the neutrophil motility
Deubelbeiss, K.A.; Keller, H.U.; Roth, P.
Schweizerische Medizinische Wochenschrift 105(47): 1591-1592
1975
ISSN/ISBN: 0036-7672 PMID: 1108184 Document Number: 86101
A 51-year-old patient exhibited severe neutropenia over a period of 12 months following lobectomy for carcinoma of the lung. Marrow neutrophil mass and marrow neutrophil production were measured quantitatively and were within normal limits. Mobilization into a skin window was absent. A defect in neutrophil motility could be demonstrated in vitro and was confirmed in vivo by poor neutrophil release from the marrow following injection of hydrocortisone; it thus represented a lazy leukocyte syndrome of the adult.