Renal complications after rifampicin
Mănescu, N.; Dumitru, S.; Gluhovschi, G.; Golea, O.; Nicolcioiu, M.; Schwarzkopf, A.; Bercovici, L.; Hoţa, F.; Hoborca, A.; Zosin, C.
Revista de Igiena Bacteriologie Virusologie Parazitologie Epidemiologie Pneumoftiziologie. Pneumoftiziologia 24(1): 35-42
1975
ISSN/ISBN: 0377-5011 PMID: 171721 Document Number: 85887
Six observations are presented of patients receiving intermitent rifampicin treatment (900 mg twice weekly) that developed acute renal failure during treatment (4 cases) or when treatment was taken up again, after an interruption of 6 months (2 cases). Following anuria of 4--14 days and nitrogen retention between 248 and 521 mg, the evolution was favourable. Clinical, biological and immunological data (anti-rifampicin antibodies were detected in 1/8 and 1/16 in 3 cases) suggest the immune origin of this type of renal accidents.