Acute renal failure, intravascular hemolysis and toxic hepatitis caused by repeated use of rifampicin (case report)
Sefer, S.; Ivanusa, M.; Kes, P.; Ratković-Gusić, I.; Vasilj, D.
Lijecnicki Vjesnik 121(4-5): 126-128
1999
ISSN/ISBN: 0024-3477 PMID: 10437356 Document Number: 6111
We report the case of a 57-year-old man treated with interrupted rifampicin therapy for urinary tract tuberculosis who experienced acute renal failure, intravascular hemolysis and toxic hepatitis. This combined adverse reactions are rare. Supportive treatment with dialysis and withdrawal of rifampicin result with complete recovery. Interrupted and intermittent therapy with rifampicin should be avoided and noncompliant patients should be given alternative treatment when possible.
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