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Anti-Proliferation and Apoptosis Induction in Breast Cancer Cells by Cratoxylum cochinchinense Extract

Innajak, S.; Nilwarangoon, S.; Mahabusarakam, W.; Watanapokasin, R.

Journal of the Medical Association of Thailand 99 Suppl. 8: S84-S89

2016

ISSN/ISBN: 0125-2208
PMID: 29901920
Document Number: 8535
Breast cancer is the most common invasive cancer in females worldwide. It was found about 37.5% in Thai To investigate the effect of Cratoxylum cochinchinense extract on anti-proliferation and apoptosis induction in breast cancer cells. Cell proliferation and cell viability assay were determined by MTT assay. Hoechst 33342 and JC-1 staining were used to determined nuclear morphological changes and mitochondrial membrane potential, respectively. C. cochinchinense extract showed anti-proliferation in MDA-MB-468 treated cells in a time- and dose-dependent manner with IC50 value of 19.19+0.8 μg/ml. In addition, C. cochinchinense extract induced nuclear condensation and apoptotic bodies in MDA-MB-468 treated cells. JC-1 staining revealed that C. cochinchinense extract induced mitochondrial membrane dysfunction. C. cochinchinense extract showed anti-proliferation and apoptosis induction properties in MDA-MB-468

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Roy, M.K.; Nakahara, K.; Na, T.V.; Trakoontivakorn, G.; Takenaka, M.; Isobe, S.; Tsushida, T. 2007: Baicalein, a flavonoid extracted from a methanolic extract of Oroxylum indicum inhibits proliferation of a cancer cell line in vitro via induction of apoptosis Die Pharmazie 62(2): 149-153
Zhang, W.; Li, Y.; Luo, J.; Zhao, X.; Xu, J.; Zhu, W.; Jiang, Y.; Fang, F. 2014: Proliferation inhibition and apoptosis induction of Juglone on human cervical cancer Caski cells Wei Sheng Yan Jiu 43(6): 959
Sun, Y.; Lin, X.; Chang, H. 2016: Proliferation inhibition and apoptosis of breast cancer MCF-7 cells under the influence of colchicine Journal of BUON: Official Journal of the Balkan Union of Oncology 21(3): 570-575
Vidhya, N.; Devaraj, S.N. 2011: Induction of apoptosis by eugenol in human breast cancer cells Indian Journal of Experimental Biology 49(11): 871-878
Guan, H-tao.; Xue, X-huan.; Wang, X-jing.; Li, A.; Qin, Z-yin. 2006: Effects of siRNA targeted to survivin in suppressing proliferation and inducing apoptosis in breast cancer MCF-7 cells Zhonghua Zhong Liu Za Zhi 28(5): 326-330
Ghoneum, M.; Seto, Y.; Sato, S.; Ghoneum, A.; Braga, M.; Gollapudi, S. 2008: Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway Anticancer Research 28(3a): 1603-1609
Chen, T.-w.; Liang, Y.-n.; Feng, D.; Tao, L.-y.; Qi, K.; Zhang, H.-y.; Wang, H.-x.; Lin, Q.-s.; Kong, H. 2013: Metformin inhibits proliferation and promotes apoptosis of HER2 positive breast cancer cells by downregulating HSP90 Journal of Buon: Official Journal of the Balkan Union of Oncology 18(1): 51-56
Mangiarotti, R.; Danova, M.; Alberici, R.; Pellicciari, C. 1997: Cell cycle kinetic effects and induction of apoptosis by all-trans retinoic acid (ATRA) in human MCF-7 breast cancer cells European Journal of Histochemistry: Ejh 41(Suppl 2): 77-78
Tang, D.G.; Li, L.; Chopra, D.P.; Porter, A.T. 1998: Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins Cancer Research 58(15): 3466-3479
Ma, X-Li.; Wang, B-Bei.; Wu, P.; Lu, Y-Ping.; Zhou, J-Feng.; Ma, D. 2009: Construction of anti-sense cDNA library of human breast cancer cells during apoptosis induced by trichostatin A and preliminary screening of essential genes Zhonghua Yi Xue Za Zhi 89(7): 480-484
Vigone, A.; Tron, G.C.; Surico, D.; Baj, G.; Appendino, G.; Surico, N. 2005: Ingenol derivatives inhibit proliferation and induce apoptosis in breast cancer cell lines European Journal of Gynaecological Oncology 26(5): 526-530
Nakamura, S.; Takeshima, M.; Nakamura, Y.; Ohtake, S.; Matsuda, T. 1997: Induction of apoptosis in HL60 leukemic cells by anticancer drugs in combination with anti-Fas monoclonal antibody Anticancer Research 17(1a): 173-179
Gao, L.; Yang, J.-r.; Peng, Y.-y.; Pan, T.-j. 2011: Effects of staurosporine on the proliferation and apoptosis of prostate cancer PC-3 cells Zhonghua Nan Ke Xue 17(10): 884-887
Bao, L.; Wang, Y.; Ma, R.; Ren, X.; Cheng, R.; B, A. 2015: Apoptosis-inducing effects of lentinan on the proliferation of human bladder cancer T24 cells Pakistan Journal of Pharmaceutical Sciences 28(5): 1595-1600
Stingl, L.A.; Sinska, A.; Landesmann, U.; Smolen, J.S. 1987: Induction of interleukin 2 receptiveness and proliferation in resting peripheral T cells by monoclonal anti-CD3 (T3) antibodies does not require the presence of macrophages Clinical and Experimental Immunology 68(1): 146-155
Sophonnithiprasert, T.; Mahabusarakam, W.; Nakamura, Y.; Watanapokasin, R. 2015: Antiproliferation and Apoptosis Induction in Colorectal Cancer Cells by Goniothalamin Journal of the Medical Association of Thailand 98(Suppl 9): S146-S151
Touma, R.; Kartarius, S.; Harlozinska, A.; Götz, C.; Montenarh, M. 2006: Growth inhibition and apoptosis induction in ovarian cancer cells International Journal of Oncology 29(2): 481-488
Yao, C.; Liu, J.; Shao, L. 2011: Rapamycin inhibits the proliferation and apoptosis of gastric cancer cells by down regulating the expression of survivin Hepato-Gastroenterology 58: 107-108
Tsuchiya, T.; Tsuno, N.H.; Asakage, M.; Yamada, J.; Yoneyama, S.; Okaji, Y.; Sasaki, S.; Kitayama, J.; Osada, T.; Takahashi, K.; Nagawa, H. 2008: Apoptosis induction by p38 MAPK inhibitor in human colon cancer cells Hepato-Gastroenterology 55(84): 930-935
Su, C-Cheng.; Chen, G-Wei.; Tan, T-Wei.; Lin, J-Gung.; Chung, J-Gung. 2006: Crude extract of garlic induced caspase-3 gene expression leading to apoptosis in human colon cancer cells In Vivo 20(1): 85-90