Obstetrico-pediatric aspects of physiopathology of lipid metabolism. I. Synthesis of the physiological bases with special regard to hormonal regulation and classification of dyslipidemias
Massobrio, M.; Benso, L.; Durando, C.
Annali di Ostetricia Ginecologia Medicina Perinatale 96(1): 3-13
1975
ISSN/ISBN: 0300-0087 PMID: 1221907 Document Number: 84734
This work is the 1st of a research program on the behavior of lipid metabolism during pregnancy and in the 1st years of life. Theories on the subject of the biochemistry of cholesterol and triglycerides are summarized and lipid physiology, particularly from the viewpoint of hormone regulation and the behavior of some important enzyme systems, is examined. Lipid transport systems, in the form of lipoproteins, is discussed, followed by a description and classification of hyper- and hypolipemia and of the relation between some forms of hyperlipemia and atherosclerosis. It is concluded that it would be very useful to obtain an early identification of subjects with a high risk of atherosclerosis in order to begin prophylactic treatment, if possible, during early infancy or even during pregnancy.