Factors affecting the kinetic assay of nitroglycerin in dosage forms
Yap, S.K.; Rhodes, C.T.; Fung, H.L.
American Journal of Hospital Pharmacy 32(10): 1039-1042
1975
ISSN/ISBN: 0002-9289 PMID: 811115 Document Number: 84222
Parameters affecting the spectrophotometric kinetic assay for nitroglycerin are described. It is shown that the assay is highly specific; results are not significantly affected by many of the tablet diluents found in commercially-available nitroglycerin tablets. Further, the assay is insensitive to glycerol, nitrate, nitrite and glyceryl dinitrates. This simple, precise and specific nitroglycerin assay is well suited for routine analysis of the drug in commercial tablets and parenteral solutions in hospital pharmacies.