Functional evaluation of endocrine areas in breast dysplasias
Orofino, G.
La Clinica Terapeutica 75(4): 385-391
1975
ISSN/ISBN: 0009-9074 PMID: 1227765 Document Number: 84176
On the basis of the known action of several hormones on the development and functions of the mammary glands, it is concluded that, in addition to an excessive estrogen action or a deficiency of progestins, as is commonly believed, several other hormonal dysfunctions may favor the appearance and development of breast dysplasia and hyperplasia. Therefore, the areas to be studied are, 1st of all, the ovaries, and, in case of negative findings, the pituitary gland, the adrenal glands, and the thyroid. Furthermore, in case of significant changes in the level of 1 or more hormones, before treating the gland to which such change is usually attributed, the physician should take into account the possibility of other alterations involving the transport or transformation and elimination of hormones (such as diseases capable of altering serum proteins or liver and kidney diseases that effect the catabolism of hormones). Breast dysplasia is predisposed subjects may be favored by alterations involving any of the hormones acting on the breast, but also by other causes, and this should be considered before resorting to hormone treatment, which, in some cases, could be useless or even harmful.