The genetic heterogeneity of hereditary human diseases
Bunimovich, L.A.
Genetika 11(10): 125-133
1975
ISSN/ISBN: 0016-6758 PMID: 1225746 Document Number: 82875
The paper deals with the probability regularities of mutations arising in the same locus (or nucleotide) in human populations. It is shown that in a population of constant size the number of such recurrent mutations tends to an equilibrium value. It is demonstrated that dynamics of this number of recurrent mutations depends on the population structure essentially. This phenomenon is illustrated by comparing non-subdivided and hierarchy populations of the same size.