Use of the system of progesterone liberation in uterol in dysfunctional uterine bleeding
Ruiz Velasco, V.; Martínez Manautou, J.; Illanes Amurrio, S.; Maqueo Topete, M.; Conde de Vargas, B.I.
Ginecologia y Obstetricia de Mexico 36(214): 115-127
1974
ISSN/ISBN: 0300-9041 PMID: 4430447 Document Number: 82530
10 patients, aged 25-46, with dysfunctional menstrual bleeding, were inserted a progesterone-releasing IUD, delivering 65 mcg. of progesterone daily. Complete examinations were carried out before insertion, and after 3 and 6 months. Amount and duration of bleeding diminished in 9 patients; 2 patients presented short periods of amenorrhea. Proliferative endometria changed in secreting endometria, while vaginal cytology with previous estrogenic activity did not change in 2 cases, or insufficiently in 2 more cases. From these results it is concluded that progesterone has a local action at endometrial level, but no systemic collateral actions, and that it can be usefully employed in controlling dysfunctional bleeding.