Anticonvulsant activity of delta9-tetrahydrocannabilol and its 11-hydroxy and 8alpha, 11-dihydroxy metabolites in the frog
Karler, R.; Cely, W.; Turkanis, S.A.
Research Communications in Chemical Pathology and Pharmacology 9(3): 441-452
1974
ISSN/ISBN: 0034-5164 PMID: 4548551 Document Number: 71857
Document emailed within 1 workday
Related Documents
Watanabe, K.; Yamamoto, I.; Oguri, K.; Yoshimura, H. 1981: Metabolic disposition of delta 8-tetrahydrocannabinol and its active metabolites, 11-hydroxy-delta 8-tetrahydrocannabinol and 11-oxo-delta 8-tetrahydrocannabinol, in mice Drug Metabolism and Disposition: the Biological Fate of Chemicals 9(3): 261-264Melby, J.C.; Dale, S.L. 1977: Role of 18-hydroxy-11-deoxycorticosterone and 16 alpha, 18-dihydroxy-11-deoxycorticosterone in hypertension Mayo Clinic Proceedings 52(5): 317-322
Löscher, W. 1981: Anticonvulsant activity of metabolites of valproic acid Archives Internationales de Pharmacodynamie et de Therapie 249(1): 158-163
Levtchenko, N.K.; Osokin, D.M.; Torgov, I.V.; Arzamastzev, A.P.; Sokolova, T.M.; Tuguntaev, G.I. 1988: High-performance liquid chromatographic analysis of the by-products of the synthesis of ethynylestradiol, mestranol, 17 alpha-hydroxy-progesterone caproate and 17 alpha-hydroxy-6-dehydroprogesterone acetate Journal of Chromatography 456(2): 427-430
Gordon, S.; Costa, L.; Incerti, M.; Manta, E.; Saldaña, J.; Domínguez, L.; Mariezcurrena, R.; Suescun, L. 1997: Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives Farmaco 52(10): 603-608
Li, L.; Li, Z.H. 1990: X-ray diffraction studies on the configuration of 2 xi, 17 alpha-diethynyl-2 xi, 17 beta-dihydroxy-A-nor-5 alpha-androstane alpha-epimer Yao Xue Xue Bao 25(6): 435-437
Pelling, J.C.; Slaga, T.J.; DiGiovanni, J. 1984: Formation and persistence of DNA, RNA, and protein adducts in mouse skin exposed to pure optical enantiomers of 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne in vivo Cancer Research 44(3): 1081-1086
Kirubagaran, R.; Joy, K.P. 1988: Inhibition of testicular 3 beta-hydroxy-delta 5-steroid dehydrogenase (3 beta-HSD) activity in catfish Clarias batrachus (L.) by mercurials Indian Journal of Experimental Biology 26(11): 907-908
Swedberg, M.D.; Jacobsen, P.; Honoré, T. 1995: Anticonvulsant, anxiolytic and discriminative effects of the AMPA antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) Journal of Pharmacology and Experimental Therapeutics 274(3): 1113-1121
Robertson, I.G.; Guthenberg, C.; Mannervik, B.; Jernström, B. 1986: Differences in stereoselectivity and catalytic efficiency of three human glutathione transferases in the conjugation of glutathione with 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene Cancer Research 46(5): 2220-2224
Leighty, E.G. 1979: Hydrolysis of 11-palmitoyloxy-delta 9-tetrahydrocannabinol to 11-hydroxy-delta 9-tetrahydrocannabinol by cholesterol esterase and a lipase Research Communications in Chemical Pathology and Pharmacology 24(2): 393-396
Takeda, M.; Takagi, T. 1980: Effects of a new bronchodilator, (alpha RS)-3-formamido-4-hydroxy-alpha-[[[(alpha RS)-p-methoxy-alpha-methylphenethyl] amino] methyl] benzyl alcohol fumarate dihydrate (BD 40A) on gastric acid secretion and gastrointestinal motility Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 76(3): 185-191
Lutsky, B.N.; Millonig, R.C.; Wojnar, R.J.; Free, C.A.; Devlin, R.G.; Varma, R.K.; Karanewsky, D.S. 1986: Androstene-17-thioketals. 2nd communication: pharmacological profiles of tipredane and (11 beta, 17 alpha)-17-(ethylthio)-9 alpha-fluoro-17-[2-(fluoroethyl)thio]-11 beta-hydroxy-androsta-1,4-dien-3-one, structurally novel 20-thiasteroids possessing potent and selective topical antiinflammatory activity Arzneimittel-Forschung 36(12): 1787-1795
Spits, H.; Paliard, X.; Engelhard, V.H.; de Vries, J.E. 1990: Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156 Journal of Immunology 144(11): 4156-4162
Roszkowski, A.P.; Garay, G.L.; Baker, S.; Schuler, M.; Carter, H. 1986: Gastric antisecretory and antiulcer properties of enprostil, (+/-)-11 alpha, 15 alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-9-oxoprosta- 4,5,13(t)-trienoic acid methyl ester Journal of Pharmacology and Experimental Therapeutics 239(2): 382-389
Frølich, A.; Nielsen, B.F.; Transbøl, I. 1990: Respective roles of 25 hydroxy-vitamin D, PTH, phosphate and renal function for the 1-alpha-hydroxylase activity in primary hyperparathyroidism Mineral and Electrolyte Metabolism 16(4): 210-215
Fischer, W. 1991: The anticonvulsant action of 5-hydroxy-L-tryptophan in various seizure models in the mouse Die Pharmazie 46(7): 540-541
Ferrick, D.A.; Gajewski, D.; Mak, T.W. 1991: First wave fetal thymocytes expressing V3J gamma 1C gamma 1-V delta 1J delta 2C delta T cell receptors are not required for alpha beta T cell receptor rearrangement and expression Advances in Experimental Medicine and Biology 292: 47-51
Stals, F.S.; Zeytinoglu, A.; Havennith, M.; de Clercq, E.; Bruggeman, C.A. 1993: Comparative effect of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine treatment on cytomegalovirus-induced interstitial pneumonitis in allogeneic bone marrow transplant recipient rats Transplantation Proceedings 25(1 Part 2): 1248-1249
Kasai, H.; Mizutani, S.; Matsumoto, K. 1973: Detection of (3H)5 alpha-androstane-3 alpha,17 beta-diol and 3H17 beta hydroxy-5 alpha-androstan-3-one in mouse testes following administration of (3H) testosterone Acta Endocrinologica 74(1): 177-185