Multiple minute digitate hyperkeratoses report of two cases with an updated review and proposal for a new classification
Ramselaar, C.; Toonstra, J.
European Journal of Dermatology Ejd 9(6): 460-465
1999
ISSN/ISBN: 1167-1122 PMID: 10491504 Document Number: 7176
Multiple minute digitate hyperkeratoses (MMDH) is a relatively rarely described disorder of keratinization of unknown origin. We noticed that MMDH has been reported in the literature under a variety of synonyms. We observed two patients with MMDH and reviewed the literature. We concluded that MMDH is a skin disorder which can be properly separated from other disorders of keratinization and classified as a distinct entity. Two forms of MMDH exist: MMDH of early onset and MMDH of late onset. Both forms are described occurring in a widespread and in a localized pattern. The early onset form may be hereditary, the late onset form may present as part of a paraneoplastic syndrome.
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