Oseltamivir therapy in two low birth-weight premature infants born to women with H1N1 influenza
Acosta, A.M.; García, I.és.; Lourdes, G.ía.; Rivera, Z.; Rivera, J.; Valcárcel, M.
Boletin de la Asociacion Medica de Puerto Rico 104(1): 32-36
2012
ISSN/ISBN: 0004-4849 PMID: 22788075 Document Number: 702532
The influenza A (H1N1) virus may cause severe illness in humans, especially children less than two years of age. The neuraminidase enzyme inhibitor, oseltamivir, is a potent medication for the management of patients with this infection. Minimal information exists regarding the immediate and long term effects of oseltamivir therapy in low birth weight premature infants born to mothers with this viral illness. This is a review of two premature male infants born to mothers with influenza A (H1N1), their presentation, clinical course, administration of oseltamivir, medical management and long term follow up through the first 18 months of life.