Survival and outcome of very low birth weight infants born in a university hospital with level II NICU
Sritipsukho, S.; Suarod, T.; Sritipsukho, P.
Journal of the Medical Association of Thailand 90(7): 1323-1329
2007
ISSN/ISBN: 0125-2208 PMID: 17710972 Document Number: 3073
Objectives: Determine the survivals, neonatal outcomes to hospital discharge, and perinatal risks of death among VLBW infants born in the Thammasat University Hospital.Material and Method. This was a retrospective longitudinal study. Data were colleted from medical charts of all neonates with a gestational age of more than 25 weeks and birth weight of less than 1500 grams, who were born in Thammasat University Hospital for a 3-year period between July 1(st), 2003 and June 30(th), 2006. Antenatal history, perinatal data, and neonatal outcome until hospital discharge were extracted and analyzed.Results: Seventy-eight neonates with a birth weight between 600-1,485 grams were analyzed Survival rate of very-low-birth-weight (VLBW) infants and extremely-low-birth-weight (ELBW) infants were 81% and 52% respectively. Respiratory distress syndrome (RDS) was the major cause of death. Major morbidity was found in 35% of survived infants to hospital discharge. Unfavorable outcome was documented in infants with a birth weight < 750 grams. Perinatal risks of mortality among VLBW infants included no use of antenatal steroids (p = 0.015), gestational age of < 28 weeks (p = 0.012), ELBW (p < 0.001), congenital abnormalities (p = 0.002), Apgar score at 5 minute.! 5 (p = 0.019), needed endotracheal intubation in the delivery room (p < 0. 001), and first temperature at NICU <= 35.0 degrees C (p = 0. 023).Conclusion: Overall survival and outcome among very-low-birth-weight infants born in Thammasat University Hospital is acceptable. The mortality and morbidity in extremely-low-birth-weight infants remained high. A continuing audit of these measures should be encouraged
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