Toxic shock syndrome--pathogenesis
González, A.; Gorbea, H.F.; Ramírez-Ronda, C.H.
Boletin de la Asociacion Medica de Puerto Rico 74(12): 383-386
1982
ISSN/ISBN: 0004-4849 PMID: 6086117 Document Number: 701501
Toxic Shock Syndrome (TSS) is a clinical phenomenom associated to menstruation and tampon use in women. As time progresses it is increasingly related to postoperative round and localized infections with Staphylococcus aureus. The criteria used to diagnose TSS includes fever, hypotension, erythroderma with desquamation, hyperemia of mucosal surfaces and multisystem dysfunction. TSS is a localized infection caused by a S. aureus strain capable of producing potent exotoxins which are responsible for the systemic manifestations of the disease. TSS is mechanically induced by abrasion to a mucosal surface that has been previously colonized with S. aureus or will be so during the disruption of mucosal integrity.
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