Streptococcus-induced syndrome of toxic shock (streptococcal toxic shock syndrome)
Köhler, W.; Nestler, J.; Knöll, H.; Schneider, J.; Schau, H.P.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 44(24): 725-731
1989
ISSN/ISBN: 0044-2542 PMID: 2698006 Document Number: 340963
Report on the first case of streptococcal toxic shock syndrome in the GDR. The patient was a 54-year-old female. One week before admission to the hospital she cut her finger. The day before admission to the hospital she presented with a painful left shoulder. Demarcation followed, and Streptococcus pyogenes (group A streptococci) was isolated from this area. The temperature rose to more than 40 degrees C and she became confused, hypotensive and anuric. There was evidence for disseminated intravascular coagulation. She died 23 h after admission. Clinical course and laboratory parameters resembles staphylococcal toxic shock syndrome, except a diarrhoea. The streptococcal strain produced a large amount of erythrogenic toxin type B (more than 20 ng/ml), but not erythrogenic toxins A or C. Erythrogenic toxins of Streptococcus pyogenes seem to play the same role in the development of streptococcal toxic shock syndrome as the toxic shock syndrome 1 (TSST-1) in staphylococcal toxic shock syndrome.