A Case of Good Quality of Life (QOL) and Favorable Response to Transarterial Chemoembolization (TACE) against Synchronous Multiple Liver Metastases
Sugimoto, K.; Sakamoto, K.; Amemiya, K.; Tsuchiya, Y.; Hagiwara, T.; Matsuzawa, H.; Makino, Y.; Motegi, S.; Kawai, M.; Ishiyama, S.; Kamiyama, H.; Takahashi, M.; Kojima, Y.; Tomiki, Y.; Kuwatsuru, R.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 46(4): 730-732
2019
ISSN/ISBN: 0385-0684 PMID: 31164517 Document Number: 699849
We report a case of good quality of life(QOL)and favorable response to transarterial chemoembolization(TACE)against synchronous multiple liver metastases. An 85-year-old man was admitted to our hospital because of melena. Colonoscopy showed multiple type 2 tumors in the sigmoid colon and upper rectum. CT and EOB-MRI examinations revealed that there were multiple liver metastases. Because of his age and surgical stress, he underwent a laparoscopic Hartmann's procedure. After the resection of the primary tumor, he received tegafur/uracil for his liver metastases. However, he discontinued receiving the drugs 2 weeks later because of the development of adverse events. Instead of systemic chemotherapy, he chose to undergo TACE. He underwent TACE with irinotecan and HepaSphereTM(BioSphere Medical)8 times for his multiple liver metastases. Consequently, all multiple liver metastases disappeared. Therefore, TACE may be useful for patients who are not suitable for systemic chemotherapy.