Relationship between diagnostic imaging features and prognostic outcomes in gastrointestinal stromal tumors (GIST)
Danti, G.; Addeo, G.; Cozzi, D.; Maggialetti, N.; Lanzetta, M.Marina.; Frezzetti, G.; Masserelli, A.; Pradella, S.; Giovagnoni, A.; Miele, V.
Acta Bio-Medica Atenei Parmensis 90(5-S): 9-19
2019
ISSN/ISBN: 0392-4203 PMID: 31085970 Document Number: 699586
Gastrointestinal stromal tumors (GISTs), the most frequent mesenchymal neoplasms of the gastrointestinal tract, are a relatively recently described entity. GISTs can occur across any age but are more common in patients older than 50 years. GISTs most commonly are in the stomach (60-70%), followed by the small intestine (20%-30%); they also rarely occur in the abdominal cavity, such as in the mesentery, the omentum and the retroperitoneum. Contrast-enhanced multi-detector computed tomography (MDCT) is the most largely used imaging modality for the localization, characterization and staging of GISTs. All patterns of enhancement on contrast-enhanced MDCT can be seen with GISTs, including hypoenhancing, isoenhancing, and hyperenhancing neoplasms. A lot of prognostication systems have been proposed for the risk stratification of GISTs. This review outlines the relationship between different diagnostic imaging features and prognostic outcomes in GISTs.