Comparative Analysis of the Efficiency of the Skin Functional Statement Correction Methods in Women with 3-Rd Degree of Photo Aging
Azaryan, H.
Georgian Medical News 2019(290): 100-107
2019
ISSN/ISBN: 1512-0112 PMID: 31322524 Document Number: 699570
The purpose of this study was to conduct a comparative analysis of the effectiveness of isolated and combined use of intradermal injections of bioreparant (hyaluronic acid modified with vitamin C, glutathione and cysteine) and platelet-rich autologous plasma on functional indicators of the face skin of women with signs of 3-rd degree of photoaging. In this study, 120 women with 3-rd degree of photoaging were examined (mean age 34.5±1.54) and divided into 3 groups in accordance with the applied therapy method (isolated and combined use of plasma therapy and bio reparation). The study of the functional parameters of the skin, including corneometry (determination of the degree of epidermal hydration), sebometry (assessment of the sebum regulating function of the epidermis), cutometry (determination of the deformation and elastic properties of the skin), TEWL (determination of the transepidermal water loss level), mexametry (assessment of skin pigmentation) and pH-metry (assessment of the skin acid-base balance) was performed in all examined patients. The obtained results testify to various shifts in functional parameters, caused by the use of various therapeutic approaches. A comparative analysis of the data obtained has provided a basis for concluding that efficacy of the autologous plasma and modified hyaluronic acid combined implementation is significantly higher compared to the isolated application of these methods.