Retrospective Examination of Usefulness and Adverse Effects of Tapentadol in Patients with Cancer Pain during Anticancer Treatment
Shikada, Y.; Emi, Y.; Kometani, T.; Ochiai, T.; Fujii, M.; Noda, Y.; Kajiwara, M.; Miyazaki, S.; Asonuma, S.; Mori, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 46(11): 1727-1731
2019
ISSN/ISBN: 0385-0684 PMID: 31748482 Document Number: 699495
We retrospectively examined 106 cases of tapentadol use in Japan in August 2014 for cancer pain at our hospital.The advantage of the opioid medication tapentadol is that its introduction is suitable in patients undergoing anti-cancer treatment because of the low incidence of gastrointestinal symptoms, with glucuronidation involved in the metabolism, and lack of interactions with other drugs.However, depending on the dosage form and presence of swallowing disorders, the administration should be considered carefully.