A Case of Advanced Gastric Cancer with Pathological Complete Response after Chemotherapy (S-1/Cisplatin)
Kohira, Y.; Ishibashi, Y.; Egawa, H.; Yube, Y.; Kaji, S.; Kanda, S.; Oka, S.; Kajiyama, Y.; Sakamoto, K.; Fukunaga, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 46(5): 929-931
2019
ISSN/ISBN: 0385-0684 PMID: 31189818 Document Number: 698569
A 68-year-old female patient presented with advanced gastric cancer and multiple hepatic tumors. Upper GI endoscopy showed a type 3 lesion in the posterior wall of the gastric body. Abdominal computed tomography revealed multiple liver metastases, and staging laparoscopy identified peritoneal dissemination. She was diagnosed with clinical Stage Ⅳ gastric cancer(cT3N2M1H1). She received 3 courses of combined chemotherapy containing S-1 and cisplatin. The therapeutic response was PR. We performed total gastrectomy with D2 lymph node dissection and splenectomy. Histopathological examination revealed no residual cancer cells, indicating pCR. She continued S-1 adjuvant chemotherapy and has remained free from recurrence for 18 months.