Relationship of HDL-C and Triglyceride with Type 2 Diabetes Mellitus in Adult Female
Salma, M.U.; Nessa, A.; Saki, S.A.
Mymensingh Medical Journal Mmj 28(2): 306-310
2019
ISSN/ISBN: 2408-8757 PMID: 31086143 Document Number: 698291
Diabetes mellitus is a complex disorder involving multiple organ systems and is the primary modifiable risk factor for heart disease. Patients with type 2 diabetes mellitus have an increased prevalence of lipid abnormalities. A timely intervention to normalize circulating lipids could decrease the probability of cardiovascular complications. Aim of the study was to assess the relationship of serum High Density Lipoprotein Cholesterol (HDL-C) and triglyceride (TG) with type 2 diabetic patients in order to compare this parameter with non-diabetic subjects. This analytical type of cross sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh from July 2017 to June 2018. A total number of 160 female subjects, age ranged from 35-65 years was included in this study. Among them, eighty (80) type 2 diabetic patients were taken as study group (Group II) and eighty (80) ages matched non-diabetic female healthy subjects were taken as control group (Group I). Data were expressed as mean±SD and statistical significance of difference among the group was calculated by student's unpaired (t) test. The mean±SD of serum HDL-C of control group and study group were 49.60±2.18mg/dl & 28.58±2.80mg/dl respectively. In study group serum HDL-C was decreased. The mean±SD of serum Triglyceride of Group I and Group II were 122.06±11.65mg/dl & 221.84±11.79mg/dl respectively. In group II serum triglyceride was increased. Serum HDL cholesterol and serum triglyceride were significant in study group in comparison with control group. Therefore, by this study we recommended that routine estimation of these parameters is important for prevention of complication related to type 2 diabetes mellitus for leading a healthy life.