Von Willebrand Factor: a Tool to Predict Severity and Prognosis in Liver Disease
Jain, M.; Vargese, J.; Sachan, D.; Venkataraman, J.
Journal of the Association of Physicians of India 66(8): 70-71
2018
ISSN/ISBN: 0004-5772 PMID: 31324089 Document Number: 697523
Von Willebrand factor (vWF) is an adhesive and multimeric glycoprotein that has a central role in primary hemostasis. v W F levels correlate with thrombosis risk and inversely with bleeding risk within the apparently healthy population. Recently, numerous publications in Indian and western literature have focussed to its role in liver diseases like acute liver failure, chronic liver disease, non cirrhotic portal hypertension and tropical infections eg. dengue. The present review encapsulates the recent advances in this aspect.