Diagnosis and management of intraductal papillary mucinous neoplasms of the pancreas
Cortegoso Valdivia, P.; Chialà, C.; Venezia, L.; Gaiani, F.; Leandro, G.; Di Mario, F.; De' Angelis, G.Luigi.
Acta Bio-Medica Atenei Parmensis 89(9-S): 147-152
2018
ISSN/ISBN: 0392-4203 PMID: 30561408 Document Number: 696737
Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are cystic lesions with malignant potential. Given their increasing incidence in the latest years, a precise characterization and management of these lesions have become more and more crucial: even though the majority of IPMN has a benign and indolent course, it is fundamental to early recognize and stratify patients in order to accurately plan a tailored follow-up and to individuate those that would benefit of surgical treatment. The aim of this paper is to highlight the most recent evidence on IPMN available in the current literature. We performed a review of the recent literature and of the recent guidelines about pancreatic cystic lesions, especially IPMN. The incidence of IPMN is now on the rise: an increasing number of patients, possibly because of the increasing diagnostic yield of imaging techniques, is being diagnosed with pancreatic cystic lesions, a great part of which are IPMN. The possibility of malignant transformation requires a careful approach to these patients, in the need of tailoring the follow-up and the therapy. A detailed diagnosis, the determination of risk factors for malignant transformation and a multisciplinary approach are of foremost importance for an effective management of IPMN.