Morphological Changes of the Urogenital System Internal Structure at Modeling of Portal Hypertension in Rats
Pylypko, I.; Halytska-Kharkhalis, O.; Henyk, T.; Flekey, N.; Panchyshyn, N.
Georgian Medical News 2018(279): 117-122
2018
ISSN/ISBN: 1512-0112 PMID: 30035733 Document Number: 695929
Portal hypertension is a constant companion of numerous diseases in gastroenterology, vascular surgery, cardiology, and hematology with grave consequences for the health and life of patients. The development of portal hypertension leads to significant violations of hemodynamics in the liver vessels and the development of arterial and venous hypertrophy, stasis of blood in the vessels of the portal tract. In the experiment on rats, portal hypertension was simulated in an original way with the following study of the peculiarities of morphological changes in the internal structure of the kidneys and gonads in males as a manifestation of a violation of systemic hemodynamics. The decrease of the renal artery throughput in portal hypertension, dystrophic changes in the epithelium against the background of venous congestion, paravazal polymorphocytic infiltration and proliferation of the connective tissue have been identified.