Contrast-Induced Acute R enal Injury After Percutaneous Coronary Interventioni in Patients with ST-Segment Elevation Myocardial Infarction
Mezhonov, E.M.; Vyalkina, Y.A.; Vakulchik, K.A.; SHalaev, S.V.
Kardiologiia 8: 5-11
2018
ISSN/ISBN: 0022-9040 PMID: 30131036 Document Number: 695696
To assess frequency and prognostic value of contrast-induced acute kidney injury (CI-AKI) after percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). We included in this prospective observational study 233 patients with STEMI. Duration of follow-up was 6 months. During this period, we traced development of CI-AKI with subsequent analysis of relation of CI-AKI to STEMI outcomes. CI-AKI was registered in 29.6% of patients. Hospital mortality was 14.5 and 6.1% among patients with and without CI-AKI, respectively (p=0.037). Mortality from cardiovascular causes during the follow-up period was 17.4 and 7.3%, respectively (p=0.021). CI-AKI was associated with increase of risk of death during hospitalization (odds ratio 2.6, 95% confidence interval 1.033-6.592, p=0.042). The development of CI-AKI was associated with glomerular filtration rate.