A Distal Bile Duct Carcinoma Patient Who Underwent Surgical Resection for Liver Metastasis
Komiyama, S.; Izumiya, Y.; Kimura, Y.; Nakashima, S.; Kin, S.; Kawakami, S.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 45(3): 560-562
2018
ISSN/ISBN: 0385-0684 PMID: 29650938 Document Number: 695063
A 70-year-old man with distal bile duct carcinoma underwent a subtotal stomach-preserving pancreaticoduodenectomy without adjuvant chemotherapy. One and a half years after the surgery, elevated levels of serum SPan-1(38.1 U/mL)were observed and CT scans demonstrated a solitary metastasis, 25mm in size, in segment 8 of the liver. The patient received 2 courses of gemcitabine-cisplatin combination chemotherapy. No new lesions were detected after chemotherapy and the patient underwent a partial liver resection of segment 8. The pathological examination revealed a metachronous distant metastasis originating from the bile duct carcinoma. Subsequently, the patient received S-1 adjuvant chemotherapy for 6 months. Following completion of all therapies, the patient survived without tumor recurrence for 3 years and 10 months after the initial operation. Thus, surgical interventions might be effective in improving prognosis among selected patients with postoperative liver metastasis of bile duct carcinoma.