Common clinical features of pediatric multiple sclerosis in Pakistan - A report of 15 cases
Javid, M.Arshad.; Mubeen, K.; Warraich, M.; Amin, N.; Mehmood, Z.
Jpma. Journal of the Pakistan Medical Association 67(11): 1764-1766
2017
ISSN/ISBN: 0030-9982 PMID: 29171579 Document Number: 693214
The aim of this note is to assess the common clinical features of paediatric multiple sclerosis (PMS) in Pakistan. For this purpose, 150 MS patients with the age range of (1-72) years and mean age (34.2±11.09) years were studied during the period 2010 to 2015 from MRI centers of Pakistan. We found 15 paediatric MS cases which had clinical course relapsing-remitting MS (11), secondary-progressive MS (3) and primary-progressive MS (1). Revised McDonald criteria 2010 of MRI was used to disseminate lesions in space and time. Sensory symptoms were found 27% in PMS patients and contributed brain area of corpus callosum, brain stem, periventricle, basal ganglia, white matter and cerebellum. Optic neuritis was the second clinical feature and its prevalence was reported 20% in paediatric patients. In conclusion, Paediatric multiple sclerosis is predicted 10 % with mean age 11.2 years in Pakistan. Sensory and optic neuritis are suggested the common clinical features of paediatric multiple sclerosis in Pakistan.