Top Abstract Purchase Related
Home
>
Node
>
Subnode

CYP1A1 rs4646422 gene polymorphisms not correlated with male infertility in Chinese Han population

Zhou, Q.; Zhu, P.-r.; Zhang, M.-c.; Zhang, J.; Jiang, W.-j.; Ni, M.-x.; Liu, S.-m.; Wu, Q.-y.; Li, W.-w.; Xu, H.-q.; Xia, X.-y.

Zhonghua Nan Ke Xue 22(5): 420-424

2016

ISSN/ISBN: 1009-3591
PMID: 27416666
Document Number: 690043
To determine the correlation of the CYP1A1 (rs4646422) gene polymorphisms with male infertility in the Chinese Han population. Using the Mass ARRAY iPLEX GOLD technique, we conducted a case-control study on theCYPlA1 (rs4646422) gene polymorphisms in 636 infertile males aged 21-49 years (case group) and 442 normal healthy men aged 23-47 years (control group) of the Chinese Han population. We analyzed the genotypes and allele frequencies in the two groups ofsubjects with the SPSS 20.0 software. Compared with the wild homozygous genotype GG, the heterozygous genotype AG (OR = 1.06, 95% CI 0.81-1.38) and homozygous genotype AA (OR = 1.11, 95% CI 0.56-2.21) showed no correlation with male infertility, nor did the mutant allele A (OR = 1.06, 95% CI 0.85-1.32) in comparison with the wild allele G. The CYP1A1 (rs4646422) gene polymorphisms might not be correlated with male infertility in the Chinese Han population.

Document emailed within 1 workday
Secure & encrypted payments

Yin, Y.-L.; Guo, Y.-M.; Zhi, H.-J.; Wu, Q.-Y.; Zhu, P.-R.; Liu, H.-H.; Xia, X.-Y. 2019: Correlation of single nucleotide polymorphisms rs995030 and rs4474514 of the KITLG gene with male infertility Zhonghua Nan Ke Xue 25(6): 529-534
Gao, L.; He, G-ping.; Dai, J.; Ma, J-zheng.; Yang, G-ying.; Qi, C-ping.; Bian, Z-ping.; Yang, D.; Zhang, J-nan. 2008: Association of thrombospondin-1 gene polymorphisms with myocardial infarction in a Chinese Han population Chinese Medical Journal 121(1): 78-81
Zhao, Y.; Ding, M.; Pang, H.; Xing, J.-X.; Xuan, J.-F.; Yao, J.; Sun, Y.-H.; Wang, B.-J. 2013: Genetic polymorphisms of four SNP loci in D5 gene of dopamine receptor in Northern Chinese Han population Fa Yi Xue Za Zhi 29(1): 37-38; 48
An, J-dan.; Li, X-yuan.; Yu, J-bo.; Zhao, Y.; Jin, Z-shun. 2012: Association between the eNOS gene polymorphisms and rheumatoid arthritis risk in a northern Chinese population Chinese Medical Journal 125(8): 1496-1499
Liu, X-Lin.; Wang, F-Sheng.; Jin, L.; Liu, M-Xu.; Xu, D-Zhong. 2003: Preliminary study on the association of chemokine RANTES gene polymorphisms with HIV-1 infection in Chinese Han population Zhonghua Liu Xing Bing Xue Za Zhi 24(11): 971-975
Pan, J.P.; Chiang, A.N.; Tai, J.J.; Wang, S.P.; Chang, M.S. 1995: Restriction fragment length polymorphisms of apolipoprotein B gene in Chinese population with coronary heart disease Clinical Chemistry 41(3): 424-429
Zhai, Z.-g.; Wang, C.; Yang, Y.-h.; Pang, B.-s.; Xiao, B.; Liu, Y.-m.; Mao, Y.-l.; Weng, X.-z. 2006: Relationship between polymorphisms of plasminogen activator inhibitor-1 promoter gene and pulmonary thromboembolism in Chinese Han population Zhonghua Yi Xue Za Zhi 86(19): 1313-1317
Zhang, Z.-H.; Wang, S.-H.; Bai, J.-X. 2017: Gene polymorphisms of estrogen receptor α correlated with hypospadias in children Zhonghua Nan Ke Xue 23(1): 61-64
Jin, M.-J.; Liu, B.; Zhang, S.-S.; Zhang, Y.-J.; Xu, M.; Ma, X.-Y.; Yao, K.-Y.; Chen, K. 2008: Application of multifactor dimensionality reduction on the interactions between gene-gene, gene-environment and the risk sporadic colorectal cancer in Chinese population Zhonghua Liu Xing Bing Xue Za Zhi 29(6): 535-539
Furuya, Y.; Akashi, T.; Fuse, H. 2004: Treatment of traditional Chinese medicine for idiopathic male infertility Hinyokika Kiyo. Acta Urologica Japonica 50(8): 545-548
Lin, S.; Li, T.; Zhu, D.; Ma, C.; Wang, Y.; He, L.; Zhu, C.; Xing, Q. 2013: The association between GAD1 gene polymorphisms and cerebral palsy in Chinese infants Tsitologiia i Genetika 47(5): 22-27
Zhou, X-J.; Yu, L.; Zhu, L.; Hou, P.; Lv, J-C.; Yu, F.; Zhang, H. 2009: Association between polymorphisms in the FCGRT gene and lupus nephritis in Chinese patients Clinical and Experimental Rheumatology 27(4): 609-614
Wang, Y.; Wang, X.; Peng, J.; Chen, L.; Cheng, J.; Nie, S.; Feng, T.; Zhao, G.; Zhao, J.; Shi, X. 2008: Short communication: SDF1-3'A gene mutation is correlated with increased susceptibility to HIV type 1 infection by sexual transmission in Han Chinese Aids Research and Human Retroviruses 24(11): 1341-1345
Chen, J-zhu.; Xie, X-dong.; Wang, X-xiang.; Tao, M.; Shang, Y-peng.; Guo, X-gang. 2004: Single nucleotide polymorphisms of the SCN5A gene in Han Chinese and their relation with Brugada syndrome Chinese Medical Journal 117(5): 652-656
Yu, Z.-H.; Chen, K.; Liu, W.; Zhai, S.-d. 2018: Patent Traditional Chinese Medicine for idiopathic male infertility: a bibliometrical study Zhonghua Nan Ke Xue 24(11): 1029-1035
Liu, J.; Zhu, H.; Zhu, X.; Dai, M.; Jiang, L.; Xu, M.; Chen, J. 2003: Estrogen receptor gene polymorphisms and bone mineral density in Chinese postmenopausal women Chinese Medical Journal 116(3): 364-367
Hu, B-Chuan.; Chu, S-Li.; Wang, J-Guang.; Wang, G-Liang.; Gao, P-Jin.; Zhu, D-Liang. 2005: No association between 3 polymorphisms of transforming growth factor beta3 gene and essential hypertension in Chinese Zhonghua Xin Xue Guan Bing Za Zhi 33(2): 127-131
Chu, C-Jing.; Yang, Y-Chun.; Wei, J-Xue.; Zhang, L. 2011: Association of nicotinic acetylcholine receptor subunit alpha-4 polymorphisms with smoking behaviors in Chinese male smokers Chinese Medical Journal 124(11): 1634-1638
Wu, B.; Liu, J.; Wang, B.; Liao, X.; Cui, Z.; Ding, N. 2018: Association on polymorphisms in LncRNA HOTAIR and susceptibility to HNSCC in Chinese population European Review for Medical and Pharmacological Sciences 22(3): 702-706
Yang, M.; Tan, H.; Zheng, J.-r.; Jiang, C.-z. 2005: Relationship between GSTM1 and GSTT1 gene polymorphisms and noise induced hearing loss in Chinese workers Wei Sheng Yan Jiu 34(6): 647-649