Protective effects of Emblica officinalis (Amla) on metal-induced lipid peroxidation in human erythrocytes
Krishnamoorthy, V.K.; Rather, I.A.
Pakistan Journal of Pharmaceutical Sciences 29(3 Suppl): 1023-1026
2016
ISSN/ISBN: 1011-601X PMID: 27383481 Document Number: 689530
The protective potential of Emblica officinalis (amla) was investigated on metal-induced lipid per oxidation in human erythrocytes. Increases in the levels of MDA and catalase activity were assessed as lipid per oxidation. In addition, glutathione peroxidase (GPX), glutathione (GSH), and ascorbic acid levels were assessed as antioxidant indices. Preliminary investigation of the extract exhibited a significant reduction in lipid per oxidation and an increase in antioxidant abilities, such as a decrease in MDA, GPx and GSH (P<0.05). A significant reduction in erythrocyte hemolysis induced by hydrogen peroxide was observed using amla extract (P<0.05). These findings show that amla extract has significant protective potential against lipid per oxidation.