Hepatic Lymphoma and Splenic Aspergillosis Mimicking Hepatosplenic Abscesses from Melioidosis in Thailand
Poovorawan, K.; Thu, A.Myint.; Sutherat, M.; Phumratanaprapin, W.; Wisedopas, N.; Luvira, V.; Chierakul, W.
Southeast Asian Journal of Tropical Medicine and Public Health 47(2): 223-226
2016
ISSN/ISBN: 0125-1562 PMID: 27244960 Document Number: 689283
We report here a case of hepatic lymphoma and splenic aspergillosis in an elderly patient with diabetes mellitus, exhibiting hepatosplenic abscesses mimicking melioidosis. Immunohistochemistry confirmed the diagnosis of a diffuse hepatic large B-cell lymphoma. Biopsy of the spleen revealed a clump of fungus with a slender shape and dichotomous branching, morphologically consistent with aspergillosis. Hepatosplenic abscesses are a common presentation in melioidosis, but this case reveals this assumption can lead to misdiagnosis. Histological and microbiological confirmation are required, especially in patients with hepatosplenic lesions.