Hemolysis and primaquine treatment. Preliminary report
Menéndez Capote, R.; Díaz Pérez, L.; Luzardo Suárez, C.
Revista cubana de medicina tropical 49(2): 136-138
1997
ISSN/ISBN: 0375-0760 PMID: 9685977 Document Number: 6887
8 patients with paludism diagnosis due to Plasmodium vivax and deficiency of glucose-6-phosphate dehydrogenase that should receive antipaludism radical treatment with primaquine were studied. It was determined that 87.5% of the patients presented hemolysis but its relation with the enzymatic activity was not significant (p > 0.05). 50% of the patients could not finish their treatment because of the appearance of important hemolysis. It is concluded that primaquine should not be used indiscriminately among those patients with deficit of glucose 6 phosphate dehydrogenase.
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