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Endothelial Dysfunction and Obstructive Lung Pathology

Titova, O.N.; Kuzubova, N.A.; Lebedeva, E.S.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 102(12): 1420-1432

2016

ISSN/ISBN: 0869-8139
PMID: 30198245
Document Number: 686977
Relationship of endothelial dysfunction and obstructive pulmonary diseases is a complex and poorly understood. Vascular endothelium is a multifunctional autonomous endocrine organ. The review discusses the various functions of the endothelium, causes, mechanisms and possible markers of endothelial dysfunction. The contribution of pulmonary vessel endothelial dysfunction in the initiation and progression of chronic obstructive pulmonary disease and asthma is considered. The existing approaches to the restoration of the structural and functional integrity of the vascular endothelium are discussed.

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