A Case of Chordoma of the Sacrum Treated with Pazopanib
Shinji, A.; Okada, S.; Nakamura, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(2): 267-269
2016
ISSN/ISBN: 0385-0684 PMID: 27067697 Document Number: 686893
A-70-year-old man with chordoma of the sacrum was treated with pazopanib (initially 400 mg/day, upto 800 mg/day). After 2 months of treatment, a significant tumor reduction was achieved and the patient was able to sit down easily. Therefore, the pazopanib therapy was continued. He had 14 months of progression-free survival.
Document emailed within 1 workday
Related Documents
Giambelli, E.; Felici, A.; Allegri, C.; Bracaglia, R. 1977: Apropos of 2 cases of chordoma of the sacrum Minerva Chirurgica 32(18): 1133-1140Ohshima, T.; Sakamoto, M.; Takasugi, S.; Matsumoto, K.; Asano, N.; Kouyama, Y. 1984: Three cases of intracranial chordoma. Typical chordoma and chondroid chordoma No Shinkei Geka. Neurological Surgery 12(5): 591-598
Cavaliere, A. 1975: A case of dorsal chordoma Archivio "de Vecchi" Per l'Anatomia Patologica E la Medicina Clinica 60(3): 689-694
Semczuk, B.; Szyszko, J.; Bartoszewicz, K. 1970: A rare case of chordoma of the pharynx Otolaryngologia Polska 24(1): 91-93
Boudaouara, T.; Mezni, F.; Ennouri, A.; Ben Jilani, S. 1991: Vertebral chordoma-- a case report La Tunisie Medicale 69(11): 655-657
Lee, Y-Yaw.; Wen-Wei Hsu, R.; Huang, T-Jen.; Hsueh, S.; Wang, J-Yi. 2002: Metastatic meningioma in the sacrum: a case report Spine 27(4): E100-E103
Van Kollenburg, J.A.P.A.C.; De Waal Malefijt, J.; Gosens, T.; Spoor, A.B.; Van der Wurff, A.A.M. 2007: Chordoma of a thoracic vertebra. A case report Acta Orthopaedica Belgica 73(6): 812-816
Eisenstein, S.M.; Levin, C.; Schmaman, A. 1975: Giant cell tumour of the sacrum. A case report South African Medical Journal 49(27): 1099-1101
Fraile Rodrigo, J.J.; Ortiz García, A.M.; Tisner Nieto, J.V.; Hernández Martín, A.; Gambo Grasa, P.; Yus Gotor, C.; de Miguel Hernández, D. 1988: Chordoma of the base of the cranium. Apropos of a clinical case Acta Otorrinolaringologica Espanola 39(4): 255-258
2011: Pharmacological sheet: pazopanib (Votrient), oral administration Journal de Pharmacie de Belgique 2011(3): 95-96
Nagao, S.; Sasayama, H.; Suzuki, K.; Tsuchimoto, M.; Yagyu, Y.; Ohashi, T.; Nishimoto, A. 1987: Transcervical and transoral approach to clival and upper cervical chordoma: a case report No Shinkei Geka. Neurological Surgery 15(11): 1207-1212
Fredrickson, B.E.; Yuan, H.A.; Miller, H.E. 1982: Treatment of painful long-standing displaced fracture-dislocations of the sacrum. A case report Clinical Orthopaedics and Related Research 1982(166): 93-95
Angelopulos, N.; Ceppi, M.; Serio, G. 1990: Sacrococcygeal chordoma: a case report. Fine needle aspiration cytologic and histopathologic findings Pathologica 82(1078): 167-171
Rampon, S.; Bussière, J.L.; Flori, B.; Doly, J.; Sauverzie, B.; Baud, J.P. 1972: Anomalies of the lumbar vertebrae and of the sacrum associated with a cul-de-sac malformation of the dura mater in Recklinghausen's disease. Apropos of a case Revue du Rhumatisme et des Maladies Osteo-Articulaires 39(5): 379-384
Spiegel, D.A.; Richardson, W.J.; Scully, S.P.; Harrelson, J.M. 1999: Long-term survival following total sacrectomy with reconstruction for the treatment of primary osteosarcoma of the sacrum. A case report Journal of Bone and Joint Surgery. American Volume 81(6): 848-855
Tonooka, T.; Takiguchi, N.; Nabeya, Y.; Takayama, W.; Ikeda, A.; Soda, H.; Chiba, S.; Hoshino, I.; Arimitsu, H.; Yanagibashi, H.; Chibana, T.; Teranaka, R.; Nagata, M. 2017: A Case of Locally Advanced Rectal Cancer Invading Posteriorly Adjacent to Sacrum Resected by Laparoscopic Low Anterior Resection Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1862-1864
Lim, G.H. 1975: Clivus chordoma with unusual bone sclerosis and brainstem invasion. A case report with review of the radiology of cranial chordomas Australasian Radiology 19(3): 242-250
Carpenter, J.L.; Stein, B.S.; King, N.W.; Dayal, Y.D.; Moore, F.M. 1990: Chordoma in a cat Journal of the American Veterinary Medical Association 197(2): 240-242
Schnyder, S.; von Flüe, M.; Vogt, B. 1987: Resection of the sacrum Der Chirurg; Zeitschrift für Alle Gebiete der Operativen Medizen 58(9): 612-618
Leeson, M.C.; Hite, M. 1989: Ganglioneuroma of the sacrum Clinical Orthopaedics and Related Research 246: 102-105