Pharmacology of bone resorption inhibitor
Menuki, K.; Sakai, A.
Nihon Rinsho. Japanese Journal of Clinical Medicine 73(10): 1634-1638
2015
ISSN/ISBN: 0047-1852 PMID: 26529923 Document Number: 685470
Currently, bone resorption inhibitor is mainly used for osteoporosis. A number of these agents have been developed. These pharmacological action are various. Bisphosphonate inhibit functions of the osteoclasts by inducing apoptosis. On the one hand, RANK-ligand inhibitor and selective estrogen receptor modulator inhibit formation of osteoclasts. It is important to understand these pharmacological action for the selection of the appropriate medicine.