Treatment of castration-resistant prostate cancer: Evidence-based clinical practice
Wang, W.; Peng, R.-x.; Shi, G.-w.; Chen, S.-y.; Ding, Q.; He, J.-y.
Zhonghua Nan Ke Xue 21(12): 1121-1124
2015
ISSN/ISBN: 1009-3591 PMID: 26817307 Document Number: 684518
To introduce the framework of evidence-based practice with a case of castration-resistant prostate cancer (CRPC) as an example. A clinical question was formulated according the clinical scenario. A systematic search was conducted for the published literature in the databases of PubMed, EMBASE, Cochrane Library, Clinical Trial Registries, and Web of Knowledge up to Dec 2014. The identified literature was reviewed for quality appraisal before the evidence was applied to clinical practice. The treatment was effective and the patient achieved disease remission. Evidence-based practice should be integrated with clinical scenario, current evidence, and patients' willingness, and follow a systematic framework.