Predictive factors for recurrence after surgery of nasal polyposis
Sellami, M.; Mnejja, M.; Masmoudi, M.; Charfeddine, I.; Hammami, B.; Ghorbel, A.
Revue de Laryngologie - Otologie - Rhinologie 136(4): 149-153
2015
ISSN/ISBN: 0035-1334 PMID: 29400036 Document Number: 684195
Endoscopic sinus surgery has become the treatment of choice in the surgical management of patients with nasal polyposis. The aim of our study is to identify the role of some epidemiological, clinical and therapeutic factors in recurrence after surgery of nasal polyposis. We conducted a retrospective study over a period of 11 years (between 2000 and 2010) including 184 patients operated for nasal polyposis after failure of prolonged medical treatment. We evaluated the impact of epidemiological and clinical factors (age, sex, asthma, Widal disease, allergy and stage of nasal polyposis at the time of surgery) and treatment (surgical technique, observance of postoperative topical steroids ) on postoperative recurrence. Nasal polyposis recurred in 26.6% of patients after an average period of 23 months. Widal disease, asthma and bad observance of the intranasal steroid therapy were significantly associated with postoperative recurrence in the univariate analysis. In multivariate analysis the bad observance of the intranasal steroid therapy was the only factor significantly associated with recurrence. Postoperative steroids prescribed routinely in our practice can effectively prevent recurrence after endonasal surgery and this result was found in both univariate and multivariate analysis.