How i treat... onychomycosis by topical therapy
Piérard, G.E.; Piérard-Franchimont, C.
Revue Medicale de Liege 70(1): 5-11
2015
ISSN/ISBN: 0370-629X PMID: 25902599 Document Number: 683958
Onychomycosis is a frequent and challenging disease to treat. Well conducted oral therapies are commonly quite effective for a short term period. However, recurrences are frequent. Topical therapies appear globally less active. Studies in this field are rare, although the promotional advertisements to the general public abound nowadays. Various microscopic fungi (dermatophytes, yeasts, molds) should be targeted by the treatment, In addition, the distinct activity conditions of both growth and quiescence of the pathogen fungi should be influenced by the treatments. This is not frequently considered by drug companies and encountered in practice. The antifungal drug penetration inside all the nail layers is important to be performed.