A Case of Successful Treatment of Metachronous Liver Metastasis from Gastric Cancer with Hepatectomy
Okada, K.; Oka, Y.; Miyake, Y.; Nakane, S.; Ueshima, S.; Higaki, N.; Hayashida, H.; Nezu, R.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 42(12): 1995-1997
2015
ISSN/ISBN: 0385-0684 PMID: 26805242 Document Number: 682853
A 77-year-old man was found to have advanced gastric cancer and underwent total gastrectomy (pT4aN2H0P0M0, Stage ⅢB). Two years after gastrectomy, we found an elevated tumor marker level, and a liver metastasis appeared in segment 5 (20 mm in diameter). He was treated with S-1/CDDP combination chemotherapy. After 2 courses of chemotherapy, the tumor marker level kept rising and a CT scan detected a progressive tumor. S-1/irinotecan combination chemotherapy was administered as second-line chemotherapy. After 6 courses of chemotherapy, the size of the liver metastasis was reduced and the tumor marker level normalized. Because lymph node metastasis or peritoneal recurrence was observed, a partial resection of the liver (S5) was performed. After the operation, he was treated with S-1 chemotherapy again for 1 year and has had no recurrence.